Natalie joined CMU and the Kingsford group in 2015 as a student in the CMU-University of Pittsburgh Ph.D. program in computational biology (CPCB). She successfully defended her dissertation on September 21, 2020 via a public video-conferencing defense. During her time at CMU, Natalie was a recipient of a Richard K. Mellon Presidential Fellowship, and was president of the graduate student association. She has also worked extensively in outreach programs such as CMU’s TechNights.
Her researched focused on development of new, innovative ways to compare and analyze the 3-dimensional structure of human genomes. Her work has been published in top computational biology conferences (e.g. ISMB) and top journals (Nuc Acids Res Genomics and Bioinformatics). A major focus of her work has been understanding the definition, role, and function of so-called “topologically associating domains” — compact regions of chromatin. For example, she was the first to provide a formal, statistical method to find regions of similar topological domain structure between two tissues or individuals.
You can find links to her papers here.